BioChaperone^® 

BioChaperone® optimizes the performance of therapeutic proteins

BioChaperone® is a Molecular Delivery System for Therapeutic Proteins.

Adocia designed the BioChaperone® platform technology from innovative polymers, oligomers and small organic compounds. By forming a physical complex with proteins, BioChaperone® protects them from enzymatic degradation and enhances their performance.

BioChaperone® improves “chaperoned” proteins’ efficency through its stabilizing and solubilizing effects:

• Acceleration of action and modification of action duration
• Enhancement of absorption and bioavailability
• Decreased dosage and frequency of administration

The molecular complex BioChaperone®-Protein spontaneously forms when both molecules are mixed in an aqueous medium. Neither heating nor use of organic solvent are needed to form the complex.

BioChaperone® brings 4 key properties to the complexed protein:

• Solubilization at physiological pH
• Protection against enzymatic degradation
• Maintained activity in presence of cells
• Stabilization during storage

Formation of a BioChaperone® Protein Complex