ADOCIA a biotechnology company dedicated to protein delivery

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“Physically glycosylating” proteins to enhance their performance

BioChaperone®: Innovative biopolymers inspired by Heparin

The capacity of heparin, a natural polysaccharide, to form molecular complexes with growth factors was discovered over a decade ago. This physical association through electrostatic interactions improves growth factor activity in three main ways:

  • Increasing growth factor solubility
  • Protecting the growth factor against enzymatic degradation
  • Extending the time of action of the growth factor

 

ADOCIA portfolio: more than 300 patented BioChaperone® molecules

BioChaperone® was “bio-inspired” by heparin with the aim of forming complexes with a large variety of proteins.

ADOCIA developed BioChaperone® in order to mimic the interactive properties of heparin with growth factors, without the anticoagulation properties specific to heparin.

The BioChaperone® platform now includes more than 300 innovative patented polymers, oligomers and small organic compounds. BioChaperone® polymers are for instance dextran-based molecules functionalized with natural amino acid and carboxylate.

Représentation de BioChaperone

BioChaperone® representation

BioChaperone® polymers, oligomers and small organic compounds can interact with proteins of interest to form physical complexes. Those interactions are reversible and do not modify the protein.

Technology

  • BioChaperone®
  • Intellectual property
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BIOCHAPERONE® TECHNOLOGY

  • “Physically glycosylating” proteins
  • A versatile platform

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ADOCIA a biotechnology company dedicated to protein delivery

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